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Dovitinib sensitivity in CAM assaysa
| RCC cell line | Treatment | Tumor engraftment rate (%) (no. of samples with tumors/total no. of samples) | Do/Ve | P value |
|---|---|---|---|---|
| TG127 | Vehicle (n = 43) | 60.5 (26/43) | 0.61 | 0.085 |
| Dovitinib (n = 27) | 37.0 (10/27) | |||
| T258 | Vehicle (n = 27) | 63.0 (17/27) | 0.32 | 0.002 |
| Dovitinib (n = 25) | 20.0 (5/25) | |||
| TG121 | Vehicle(n = 31) | 64.5 (20/31) | 0.49 | 0.012 |
| Dovitinib (n = 32) | 31.2 (10/32) |
List of sunitinib-resistant cell lines evaluated for dovitinib sensitivity in CAM assays.
