Table 2.
TWIST1 and BMI1 expression in cancer chemoresistance
| Cancer type | Model | Species | Over-expressing effector | Chemotherapeutic drugs | Chemoresistance | Reference | |
|---|---|---|---|---|---|---|---|
| Twist1 | Bmi1 | ||||||
| Brain cancer | Astrocyte | Human | + | - | Paclitaxel | Yes | [96] |
| Nasopharyngeal cancer | HNE1-T3 | Human | + | - | Taxol, Vincristine | Yes | [97] |
| Tongue cancer | CAL27, SCC15, SCC25 | Human | + | + | Cisplatin | Yes | [98, 99] |
| Breast cancer | MCF-7, MDA-MB-231, MCF-7/TamR | Human | + | - | Paclitaxel, Tamoxifen | Yes | [109], [94] |
| MCF-7 | Human | - | + | Doxorubicin | [100] | ||
| Lung cancer | A549, NSCLC cells | Human | + | - | Cisplatin | Yes | [101, 102] |
| Hepatocellular carcer | SK-HEP-1, SMMC-7721 | Human | - | + | 5-Fluorouracil | Yes | [103] |
| Chronic myeloid leukemia | CML cells | Human | + | - | Imatinib | Yes | [95] |
| Osteosarcoma | SAOS-2 | Human | - | + | Cisplatin | Yes | [40] |
| Pancreatic cancer | MiaPaCa2 | Human | - | + | Gemcitabine | Yes | [104] |
| Ovarian cancer | A-2780, CP-70 | Human | - | + | Cisplatin | Yes | [105] |
| Cervical cancer | Hela cells | Human | + | - | Cisplatin | Yes | [46] |
| Prostate cancer | LNCaP, DU145, PC3 | Human | + | - | Taxol | Yes | [107] |
| LNCaP, SCC25 | Human | - | + | Docetaxol | [108] | ||
+ means positive; - means negative