Table 7.
Multivariate analysis of prognostic factors associated with overall survival.
| Variable | HR (95% C.I.) |
P - value |
|---|---|---|
| HER2 status Overexpressed vs. negative |
0.219 (0.089 - 0.542) |
0.001 |
| HR status Positive for either vs. negative for both |
0.415 (0.180 - 0.960) |
0.040 |
| CD3+ CD4+ High vs. low |
0.494 (0.227 - 1.075) |
0.075 |
| CD3+ CD8+ IFN-γ High vs. low |
0.433 (0.202 - 0.930) |
0.032 |
* all immune cells subpopulation were dichotomized as “low” or “high” based on median value of percentage of immunes cells in all patients. All hazard ratios are based on comparison of “low” vs. “high” groups.
HR = hazard ratio.