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Effects of siEphA2 on cell migration and invasion in PC3 and DU-145 cells. (A) Wound-healing assay: cell migration was significantly inhibited in response to silencing of EphA2 at 6 hours (PC3) and 12 hours (DU-145). (B) Transwell invasion assay: cell numbers on the lower side of the membrane, reflecting transmembrane invasion, were significantly reduced after EphA2 silencing by EphA2 siRNA compared with control siRNA. (Original magnification ×100, bar: 20µm).
