Table 3.

Multivariate Cox-regression analysis for OS and PFS.

Factors	OS				PFS
	HR	95%CI	P		HR	95%CI	P
Age(<50 vs.≥50)	0.966	0.260-3.591	0.958		1.223	0.603-2.479	0.577
Tumor size, cm (≤2 vs. >2)	0.492	0.128-1.900	0.304		0.744	0.364-1.649	0.507
Tumor Grade (Ivs. IIvs.III)	0.904	0.209-3.914	0.893		1.344	0.670-2.698	0.405
Node statue(cN-vs.cN+)	5.779	0.616-54.212	0.125		2.995	1.196-7.500	0.019
ER status( - vs. +)	0.089	0.009-0.921	0.042		0.495	0.191-1.281	0.147
PR status( - vs. +)	1.080	0.131-8.885	0.943		1.132	0.451-2.842	0.792
HER-2 status( - vs. +)	0.083	0.008-0.835	0.035		0.541	0.245-1.193	0.128
PLK4(low vs. high)	4.903	0.791-30.414	0.088		2.929	1.340-6.405	0.007