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UBE2D3 knockdown confers esophageal cancer cells to radioresistance. Each group was irradiated with graded doses of 0, 1, 2, 4, 6, 8, 10 Gy. After 14 days of incubation, the colonies were fixed and stained. Those colonies containing more than 50 cells were scored as viable colonies. These data were fit into the sing-hit multi-target model, and survival curves for each group were demonstrated using GraphPad prism 5.0 software.
