Table 2.
Percent visualization of the features of the posterior vitreous and vitreoretinal interface in healthy non-diabetic control eyes, diabetic eyes without retinopathy and diabetic eyes with different stages of retinopathy using vitreous enhanced three-dimensional swept-source optical coherence tomography imaging. n represents the number of eyes. p values represent the results of one-way analysis of variance. Significant p values are in bold.
FEATURE OBSERVED | % of Healthy Non-Diabetic Eyes with Feature (n=22) | % of Diabetic Eyes without Retinopathy with Feature (n=20) | % of Eyes with NPDR with Feature (n=21) | % of Eyes with PDR with Feature (n=20) | % of Eyes with DME with Feature (n=27) | p value |
---|---|---|---|---|---|---|
| ||||||
1. Bursa Premacularis | 17/22, 77% | 15/20, 75% | 14/21, 67% | 13/20, 65% | 17/27, 63% | 0.22 |
2. Area of Martegiani | 16/22, 73% | 14/20, 70% | 13/21, 62% | 13/20, 65% | 15/27, 56% | 0.09 |
3. Posterior vitreous cortex (hyaloid) detachment | 18/22, 82% | 17/20, 85% | 18/21, 86% | 17/20, 85% | 23/27, 85% | 0.18 |
4. Thick posterior hyaloid | NA | 0/20, 0% | 4/21, 19% | 11/20, 55% | 11/27, 41% | p=0.0001 |
5. Vitreoschisis | 6/22, 27% | 9/20, 45% | 10/21, 48% | 13/20, 65% | 17/27, 63% | p=0.007 |
6. Adhesions (pegs) between the detached posterior hyaloid and inner retinal surface | 0/20, 0% | 0/20, 0% | 1/21, 4% | 11/20, 55% | 11/27, 41% | p=0.0001 |
7. Vitreous clumping | 11/22, 50% | 11/20, 55% | 13/21, 62% | 13/20, 65% | 18/27, 67% | 0.10 |
Abbreviations: NPDR, non-proliferative diabetic retinopathy; PDR, proliferative diabetic retinopathy; DME, diabetic macular edema; NA, not applicable