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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Circ Heart Fail. 2016 Jun;9(6):10.1161/CIRCHEARTFAILURE.115.003011 e003011. doi: 10.1161/CIRCHEARTFAILURE.115.003011

Figure 5. Twelve weeks of treatment with sildenafil improves pulmonary vascular distensibility in patients with heart failure and reduced ejection fraction.

Figure 5

Sildenafil treatment was associated with a 24.6% increase in distensibility (n=14, P=0.015) while no appreciable change in distensibility was observed in the placebo-treated group (n=12). Treatment with a selective pulmonary vasodilator can therefore improve pulmonary vascular distensibility.