Table 3. Comparison of chronic dialysis patients with high and low medication adherence status.
Clinical features | High adherence (n = 8) | Low adherence (n = 43) | p value |
---|---|---|---|
Demographic profiles | |||
Age (years) | 71.1 ± 9.3 | 67.4 ± 12.2 | 0.42 |
Gender (male %) | 4 (50) | 18 (42) | 0.68 |
Duration of dialysis (years) | 4.5 ± 4.1 | 3.2 ± 2.5 | 0.23 |
Monthly disposable income (higher than 300 USD) | 5 (63) | 19 (44) | 0.35 |
Comorbidities (%) | |||
Diabetes mellitus | 4 (50) | 22 (51) | 0.95 |
Hypertension | 7 (88) | 39 (91) | 0.79 |
Cirrhosis | 1 (13) | 3 (7) | 0.6 |
Heart failure | 2 (25) | 9 (21) | 0.8 |
Malignancy | 2 (25) | 4 (9) | 0.21 |
Dialysis comorbidity index | 2 ± 1.9 | 1.6 ± 1.8 | 0.52 |
Etiology of ESRD (%) | 0.81 | ||
Diabetic nephropathy | 3 (38) | 18 (42) | |
Chronic glomerulonephritis | 1 (13) | 3 (7) | |
Miscellaneous | 0 (0) | 7 (16) | |
Unknown | 4 (50) | 15 (35) | |
Laboratory parameters | |||
Biochemistry and electrolytes | |||
Blood Urea Nitrogen (mg/dL) | 73.5 ± 13.2 | 82.2 ± 20.8 | 0.26 |
Creatinine (mg/dL) | 10.7 ± 2.2 | 10.6 ± 2.5 | 0.99 |
Sodium (meq/L) | 136 ± 4.1 | 135 ± 3.9 | 0.61 |
Potassium (meq/L) | 4.8 ± 0.8 | 4.7 ± 0.7 | 0.65 |
Calcium (mg/dL) | 8.6 ± 0.9 | 9 ± 0.8 | 0.25 |
Phosphate (mg/dL) | 4.3 ± 1.3 | 5.5 ± 1.5 | 0.06 |
Calcium-phosphate product | 37.9 ± 3.7 | 49.1 ± 13.5 | 0.04 |
Nutrition | |||
Albumin (mg/dL) | 3.8 ± 0.4 | 3.8 ± 0.3 | 0.97 |
Glucose (mg/dL) | 87.5 ± 19.9 | 110.6 ± 39.1 | 0.11 |
Total cholesterol (mg/dL) | 154 ± 41 | 158 ± 40 | 0.77 |
Total triglyceride (mg/dL) | 119 ± 87 | 165 ± 111 | 0.28 |
Anemic profile | |||
Hemoglobin (g/dL) | 9.3 ± 0.4 | 9.8 ± 1.4 | 0.35 |
Ferritin (ng/mL) | 529 ± 172 | 670 ± 852 | 0.65 |
Transferrin saturation (%) | 31.7 ± 16.6 | 27.6 ± 14.8 | 0.48 |
Dialysis adequacy | |||
Single pool Kt∕V | 1.6 ± 0.2 | 1.6 ± 0.3 | 0.99 |
Urea reduction ratio (%) | 75 ± 3.5 | 75 ± 6.3 | 0.9 |
Notes.
Abbreviations
- ESRD
- End-stage renal disease
- USD
- United States Dollars