Fig. 2.
In vivo luminescence lymph node imaging. (a) Bioluminescence imaging of lymphatic basins in a mouse injected with QD-Nluc intradermally in a hind paw. (b) Fluorescence image of lymph nodes excised from the mouse injected with QD-Nluc in four paws (see Fig. S2); L, left; PO, popliteal lymph node; LU, lumbar lymph node; IL, iliac; AX, axillary lymph node; R, right. (c–d) Histological images of lymph node slices from a mouse in (a); (c) PO lymph node from injected mouse exhibited bright signal from QD705 (red) whereas no significant emission from QD705 was observed in PO lymph node from non-injected mouse (d). DAPI (blue) represents nuclease, scale bar: 20 μm.