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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: NMR Biomed. 2016 May 26;29(7):978–984. doi: 10.1002/nbm.3557

Figure 5. Biochemical changes in BAT in heart failure.

Figure 5

Hematoxylin and eosin staining of BAT in a control mouse (A) and a mouse with heart failure (B). The size of the lipid globules (white areas on the slide) inside the adipocytes is decreased in heart failure, suggesting increased lipolysis. (C) A significant increase in UCP1 mRNA (* p < 0.05) is seen in the BAT of mice with heart failure, suggesting increased BAT activity. UCP1= Uncoupling Protein 1; White bar 100μm, BAT = Brown Adipose Tissue.