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. 2016 Jun 17;11(6):e0157830. doi: 10.1371/journal.pone.0157830

Fig 3. Evaluation of NK cell CD16a polymorphism on cetuximab induced ADCC.

Fig 3

Differences in cetuximab induced ADCC between NK cells expressing V/V and V/F polymorphic versions of CD16 were analyzed. Natural cytotoxicity and NK cell CD16a mediated degranulation in the absence and presence of cetuximab coated A431 cells are shown in Fig A and B. Columns are mean of triplicate values; with bars showing SD. Data are from independent experiments performed in triplicates from 3 V/V and 3 V/F donors. Mean ± SD for each significant condition are represented as p = <0.05 *, <0.01 **, <0.005 ***, <0.001 ****.