Table 1. Number of genes and transcript isoforms analyzed and differentially expressed between microglia and macrophages within and between IDO1-knockout (KO) and wild type (WT) mice.
| Comparison | Gene | Transcripts Isoform | ||
|---|---|---|---|---|
| Analyzed | DE or Unique | Analyzed | DE or Unique | |
| Microglia IDO1-KO vs. Microglia WT | 14,981 | 103 | 27,880 | 108 |
| Macrophages IDO1-KO vs. Macrophage WT | 13,074 | 137 | 24,813 | 144 |
| Overlap between previous two comparisons | 8 | 10 | ||
| Microglia IDO1-KO vs. Macrophages IDO1-KO | 15,237 | 9,956 | 28,674 | 11,423 |
| Microglia WT vs. Macrophages WT | 15,287 | 9,860 | 29,110 | 11,113 |
| Overlap between previous two comparisons | 9,293 | 10,865 | ||
| Unique to Macrophage WT | 23 | 42 | ||
| Unique to Microglia WT | 236 | 421 | ||
| Unique to Macrophage IDO1-KO | 16 | 45 | ||
| Unique to Microglia IDO1-KO | 221 | 358 | ||
DE1: differentially expressed genes or transcript isoforms (FDR-adjusted P-value < 0.05) or uniquely detected in either cell type.