. 2016 Jun 17;11(6):e0157727. doi: 10.1371/journal.pone.0157727

Table 2. Most extreme differentially expressed genes (|log₂(fold change)| > 6, FDR-adjusted P-value < 5.0 x 10⁻⁵) between microglia and macrophages in wild type mice.

Gene Symbol	Gene Name	Log₂(Macrophage/Microglia)	Literature Review Reference
Slc2a5	solute carrier family 2 (facilitated glucose transporter), member 5	-12.95	[7,42]
Gpr56	G protein-coupled receptor 56	-12.50	[7,42]
Olfml3	olfactomedin-like 3	-12.45	[7,42]
Siglech	sialic acid binding Ig-like lectin H	-11.64	[7,42]
Crybb1	crystallin, beta B1	-10.47	[7,42]
S100a9	S100 calcium binding protein A9 (calgranulin B)	-10.02	[7]
Cask	calcium/calmodulin-dependent serine protein kinase	-9.77	[41]
Serpine2	serine (or cysteine) peptidase inhibitor, clade E, member 2	-8.60	[40,42]
Ang	angiogenin, ribonuclease, RNase A family, 5	-8.37	[42]
Hpgd	hydroxyprostaglandin dehydrogenase 15 (NAD)	-7.65	[7]
Rab3il1	RAB3A interacting protein (rabin3)-like 1	-7.49	[42]
Fosb	FBJ osteosarcoma oncogene B	-7.31	[43]
Lag3	lymphocyte-activation gene 3	-7.25	[42]
S100a8	S100 calcium binding protein A8 (calgranulin A)	-7.20	[7]
F11r	F11 receptor	-6.95	[42]
Fscn1	fascin homolog 1, actin bundling protein	-6.16	[42]
Wfdc17	WAP four-disulfide core domain 17	6.38	[44]
Cxcl1	chemokine (C-X-C motif) ligand 1	7.33	[3]
Alox15	arachidonate 15-lipoxygenase	8.05	[7]
Ccl24	chemokine (C-C motif) ligand 24	8.09	[45]
Clec4d	C-type lectin domain family 4, member d	8.45	[46]
Retnla	resistin like alpha	9.29	[7]
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	10.00	[47]
Lyz1	lysozyme 1	10.89	[48]
Cd5l	CD5 antigen-like	11.13	[7]
Cxcl13	chemokine (C-X-C motif) ligand 13	11.75	[7]

Table 2. Most extreme differentially expressed genes (|log2(fold change)| > 6, FDR-adjusted P-value < 5.0 x 10−5) between microglia and macrophages in wild type mice.