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Left: ONM expansion observed in HeLa cells with a disrupted LINC complex [(Crisp et al., 2006)]. Middle: Normal NE spacing in C. elegans nuclei lacking a functional LINC complex [(Cain et al., 2014)]. Right: Increase in NE spacing at the anterior and posterior ends of unc-84 (SUN) mutant muscle cell nuclei [(Cain et al., 2014)].
