Fig 1. HCV⁺ individuals have fewer blood-derived naïve CD8⁺ T-cells and a lower expression of CD127 on central memory cells than HCV^- controls.

CD8⁺ T-cell subset distribution was determined by CD45RA and CCR7 staining in (A) controls (n = 10) and (B) HCV infection (n = 12). (C) Subset distribution data for controls and HCV-infected individuals are graphically represented as means (T_N p = 0.006). (D) The expression of CD127 was measured on blood-derived bulk CD8⁺T-cells (control n = 30, HCV⁺ n = 50) and their subsets (control n = 10, HCV⁺ n = 12) and presented as (E) percentage (T_CM p = 0.02, unpaired Student’s t-test) and (F) mean fluorescence intensity of CD127 expressing cells (error bars represent ±S.D.).