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. 1981 Dec;44(12):1129–1135. doi: 10.1136/jnnp.44.12.1129

Levels of enolase and other enzymes in the cerebrospinal fluid as indices of pathological change

Janice A Royds *, Walter R Timperley †, Christopher B Taylor *
PMCID: PMC491233  PMID: 7334408

Abstract

The activities of enolase, aldolase, pyruvate kinase, lactate dehydrogenase and creatine phosphokinase were measured in cerebrospinal fluid of 121 patients presenting with a range of disorders of the central nervous system. The results from 41 patients undergoing myelography were used as controls. An assessment was made of the relative merits of these five enzymes as markers of brain damage with special reference to brain tumours. Enolase was the most sensitive marker of pathological change and was the only enzyme raised in the CSF of patients with low grade astrocytomas.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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