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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Free Radic Biol Med. 2016 Apr 9;96:34–44. doi: 10.1016/j.freeradbiomed.2016.04.003

Figure 3. NaV1.5 expression was downregulated by ΔN-β-catenin in HL-1 cells.

Figure 3

HL-1 cells were infected with adenovirus-ΔN-β-catenin and adenovirus-lacz for 48 hours. (A) Western blot was performed on the protein extract from these cells. The result showed that expression of ΔN-β-catenin, a stabilized form of β-catenin significantly suppressed the expression of NaV1.5 protein (p<0.05), compared to the lacz control group. (B) RT-PCR analysis was performed on the total RNA extracted from these cells and the results showed that the mRNA level of NaV1.5 was significantly decreased by ΔN-β-catenin (p<0.01) compared to the lacz control group. *p<0.05 and ** p<0.01; n=3 batches of cells from 3 independent experiments carried on separate occasions for each group.