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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Free Radic Biol Med. 2016 Apr 9;96:34–44. doi: 10.1016/j.freeradbiomed.2016.04.003

Figure 6. Conservative TCF4 DNA binding sites in the SCN5a promoter.

Figure 6

(A) The proximal region (2308 bp upstream) of SCN5a promoter harbors four TCF4 binding sequences. (B) VISTA plot showing the sequences of these four potential binding sites (#1, #2, #3 and #4) in multiple species, including mouse, rat, dog, horse and human. #3 and #4 are more conservative than #1 and #2 potential binding sites.