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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Free Radic Biol Med. 2016 Apr 25;96:78–88. doi: 10.1016/j.freeradbiomed.2016.04.011

Fig. 3.

Fig. 3

Results of Fpg-sensitive quantitative real time PCR analysis of oxidative DNA damage in D-loop and coding regions of mtDNA from normoxic (N) rat pulmonary artery endothelial cells and cells exposed to hypoxia for 0.5, 1, 2, 3, 6 and 24 hours (H0.5 – H24). The ratio of PCR product accumulation in treated and untreated with Fpg samples is indicative of oxidative DNA damage. Mean ± SE, N = 3, *P < 0.05, significantly different from normoxic controls.