Table 2. Determinants of post-prandial lipid excursions.

Magnitude of effect of GFR, HOMA-IR, fasting ApoC-III, and proteinuria on plasma excursions (iAUC) of TG and of chylomicrons (ApoB48). Unadjusted refers to univariate effects. Adjusted (1) refers to the model with both GFR and HOMA-IR, and Adjusted (2) refers to the model with GFR, HOMA-IR, and fasting Apo-CIII. In the last model, Apo-C-III itself was not a significant determinant.

Magnitude of Effects on TG Excursion (unadjusted)			Adjusted(1)		Adjusted(2)
Variable	Change iAUC of TG	95% CI	Change iAUC of TG	95% CI	Change iAUC of TG	95% CI
GFR: each 10 ml/min/1.73m2 lower	17% higher (p < 0.05)	4 – 33 %	17% higher (p<0.005)	7 – 29 %	18% higher (p=0.01)	5 – 33 %
HOMA-IR: Each ½ unit higher	16% higher (p < 0.001)	3 – 29 %	16% higher (p<0.005)	15 – 17 %	16% higher (p=0.03)	1 – 33 %
Fasting ApoC-III: each mg/dL higher	12% higher (p < 0.005)	4 – 20 %	not in model		not statistically significant
Proteinuria: each 50% higher	16% higher (p<0.005)	6 – 26 %	not in model		not in model
Magnitude of Effects on apoB48 Excursion (unadjusted)			Adjusted(1)		Adjusted(2)
Variable	Change iAUC of ApoB48	95% CI	Change iAUC of ApoB48	95% CI	Change iAUC of ApoB48	95% CI
GFR: each 10 ml/min/1.73m2 lower	16% higher (p < 0.05)	1 – 33 %	16% higher (p = 0.01)	4 – 30 %	19% higher (p = 0.02)	3 – 36 %
HOMA-IR: Each ½ unit higher	16% higher (p < 0.005)	3 – 30 %	16% higher (p < 0.01)	5 – 28 %	19% higher (p = 0.03)	2 – 40 %
Fasting ApoC-III: each mg/dL higher	12% higher (p < 0.01)	3 – 20 %	not in model		not statistically significant
Proteinuria: each 50% higher	15% higher (p < 0.01)	4 – 27 %	not in model		not in model