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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Toxicol Pathol. 2016 Mar 18;44(5):738–748. doi: 10.1177/0192623316636717

Figure 2.

Figure 2

Morphology of liver and hepatocellular alterations in Fundulus heteroclitus. A, normal parenchyma, note uniformity of hepatocytes and their staining. B-F altered liver. B, basophilic focus (bf); v, sections through veins. Due to the absence of overt hepatopancreas, venous profiles cannot be identified as portal (afferent) or hepatic (efferent). C, clear cell focus; arrows point to border of lesion; v, vein. D, mixed focus composed of basophilic focus (bf) and microvesicular vacuolation (m) surrounding the focus. E, clear cell adenomas (a1 and a2) are separated by a band of normal-appearing tissue. F, lymphocyte aggregate (L) in hepatic parenchyma near bile ductules (bd); s, sinusoid; venous profile at upper left of field shows portion of exocrine pancreatic tissue (p), likely indicating portal vein. All scale bars 10 μm. 20X, H&E.