Skip to main content
. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Acta Neuropathol. 2016 Apr 8;132(1):59–75. doi: 10.1007/s00401-016-1572-y

Fig. 10.

Fig. 10

Prevention of motor cortical neuronal cell loss in mice overexpressing α-synuclein in oligodendrocytes by benztropine. a Representative images depict NeuN-positive neuronal cells within the motor cortex of non-transgenic controls (NTG) and α-synuclein transgenic mice (MBP29) treated with vehicle (veh) or benztropine (BT). Scale bar: 20μm. b Densities of motor cortical neurons are shown (n = 5). In vehicle-treated MBP29 mice, a significant reduction in neuronal cell density was observed. Benztropine treatment prevented the loss of cortical neurons in MBP29 mice. Data are shown as mean ± standard error of mean. ANOVA: *p < 0.05. T-test: ##p < 0.01.