Table 1.

Median survival of experiment mice (days)

	HepG2 (n = 6)	A549 (n = 6)	HHCC (n = 6)
rM1H	60.5 ± 18.8	23 ± 4.9	19.5 ± 5.7
rM3H	30 ± 16.5	56 ± 13	29.5 ± 7.6
rMMH	58.5 ± 19.3*$	53 ± 15*^	29.5 ± 8.6*
PBS	19.5 ± 4.6	20.5 ± 3.7	25.5 ± 4.4
UnHuM	13 ± 3.3	12.5 ± 4.1	9.5

In tumor challenge test, rMMH vaccinated mice presented the obvious survival time with HepG2 and A549 cells transplanting. Even in HHCC group the median survival of rMMH vaccinated mice was superior to others

* p < 0.05 vs. PBS group and UnHuM group

^ p < 0.05 vs. rM1H

^$ p < 0.05 vs. rM3H group