Table 1.

Parameters used in Figures 1–5 of the main paper (see also Tables 2–3). ${\mathrm{\Omega }}_{-}$ (${\mathrm{\Omega }}_{+}$) is the rate of switching from the active to the quiescent (from the quiescent to the active) state. The resting potential corresponding to the active and quiescent states is $\overline{u}$ and $-\overline{u}$, respectively. ${\overline{\mathrm{\Sigma }}}_{ii}$ (${\overline{\mathrm{\Sigma }}}_{ij}$) is the posterior variance (covariance) of the presynaptic membrane potential fluctuations in a given state where $\overline{\mathrm{\Sigma }}=\frac{\mathbf{Q}\tau }{2}$. τ_refr is the length of the refractory period and ${\mathit{\text{p}}}_{\mathrm{rel}}$ is the baseline transmission probability in these synapses (13, 49).

DOI: http://dx.doi.org/10.7554/eLife.10056.007

		Figure 1	Figure 2		Figure 3		Figure 4	Figure 5
parameter	unit	B,C	A,B	C,D	A	B	A-D	ind	cor2	NC	HP
${\mathrm{\Omega }}_{-}$	Hz	10	–	10	10	–	10	–	–	10	10
${\mathrm{\Omega }}_{+}$	Hz	10	–	0.27	0.67	–	0.67	–	–	4	0.027
$\overline{u}$	mV	2.4	0	2.3	2.3	0	2.3	0	0	10	2.3
$\tau$	ms	20	20	20	20	20	20	20	20	20	20
${\overline{\mathrm{\Sigma }}}_{ii}$	mV${}^2$	1	16	4	1	1	1	1	1	10	1
${\overline{\mathrm{\Sigma }}}_{ij} \forall i\ne j$	mV${}^2$	0	0.5	0.5	0	0.5	0	0	*	5	0.5
$g$	Hz	1	1	1	5.3	0.5	5	0.5	0.5	1	2
$\beta$	mV${}^{-1}$	1	0.4	0.4	0.5	0.4	0.4	1	2	0.1	0.6
${\tau }_{\text{refr}}$	ms	3	3	3	1	3	1	3	3	3	3
${\mathrm{p}}_{\mathrm{rel}}$	–	1	1	1	1	1	1	1	1	0.5	0.2
$N$	–	20	70	20	10	10	10	+0†	+20†	*	*
${\tau }_{\text{post}}$	ms	0	10	10	0	0	0	*	*	*	*
$w_i$	–	$1/N$	$1/N$	$1/N$	$1/N$	$1/N$	$1/N$	*	*	*	*

 *These parameters were fitted to experimentally recorded dendritic responses, see Figure 5—figure supplement 1. ^†The numbers 0 and 20 indicated here are in addition to the number of stimulated synaptic sites in the experiment. For the ind model, this number does not affect the predictions, for the cor2 model its effects could phenomenologically be incorporated into which we chose to fit instead.