Table 5.
Multivariate Hazard Ratios (AHR) for breast cancer mortalityb, SEER 2000–2010
| HR Subtype AHR (95 % CI)a |
SES AHR (95 % CI)b |
HCA AHR (95 % CI)c |
Fully adjusted AHR (95 % CI)d |
|
|---|---|---|---|---|
| Race/ethnicity | ||||
| NH-White (referent) | – | – | – | – |
| NH-Black | 1.42 (1.39–1.44) | 1.50 (1.47–1.54) | 1.56 (1.53–1.59) | 1.39 (1.36–1.43) |
| Hispanic | 1.04 (1.01–1.07) | 1.05 (1.02–1.08) | 1.07 (1.04–1.10) | 1.05 (1.03–1.08) |
| Age at diagnosis | ||||
| 40–44 (referent) | – | – | – | – |
| 45–54 | 1.01 (0.98–1.05) | 1.00 (0.96–1.04) | 1.00 (0.97–1.04) | 1.01 (0.98–1.05) |
| 55–64 | 1.29 (1.25–1.34) | 1.25 (1.21–1.30) | 1.25 (1.21–1.30) | 1.29 (1.24–1.33) |
| 65–74 | 2.03 (1.96–2.10) | 1.90 (1.84–1.97) | 1.91 (1.84–1.98) | 2.02 (1.95–2.09) |
| 75+ | 4.69 (4.54–4.85) | 4.30 (4.16–4.44) | 4.32 (4.17–4.46) | 4.69 (4.53–4.85) |
| Breast cancer hormone-receptor subtype | ||||
| HR+ (referent) | – | – | ||
| HR− | 1.91 (1.88–1.94) | 1.90 (1.87–1.93) | ||
| County-level socio-economic status† | ||||
| % Black population (SD = 13.24) | 0.99 (0.98–0.99) | 1.00 (0.99–1.01) | ||
| % Unemployed (SD = 2.20) | 0.99 (0.98–1.00) | 1.01 (1.00–1.02) | ||
| % Less than 9th grade education (SD = 4.74) |
0.98 (0.97–0.99) | 1.00 (0.99–1.02) | ||
| % Families below poverty level (SD = 4.75) |
1.09 (1.07–1.10) | 1.07 (1.05–1.09) | ||
| County-level healthcare access† | ||||
| % No health insurance (SD = 4.68) | 1.01 (1.01–1.02) | 0.94 (0.93–0.96) | ||
| # Oncology hospitals per million (SD = 10.08) | 1.01 (1.01–1.02) | 1.00 (1.00–1.01) | ||
| # Medical doctors per million (SD = 520.55) | 0.94 (0.92–0.95) | 0.95 (0.94–0.97) | ||
| # OB GYN per million (SD = 70.47) | 1.01 (0.99–1.02) | 0.99 (0.98–1.01) |
AHR adjusted hazard ratios
Bold indicates significance p value ≤0.05
a
Adjusted for race, age, SEER registry, surgical treatment, radiation therapy, and late-stage diagnosis
b
Adjusted for race, age, SEER registry, surgical treatment, radiation therapy, late-stage diagnosis, and SES
c
Adjusted for race, age, SEER registry, surgical treatment, radiation therapy, late-stage diagnosis, and HCA
d
Adjusted for race, age, SEER registry, surgical treatment, radiation therapy, late-stage diagnosis, SES and, HCA
†
HRs associated with standard deviation increase