Table 1.
Metabolite concentrations in fronto-parietal GM and WM using BASE-SLIM (top) and MRSI regression analyses (bottom). All concentrations were determined using unsuppressed water signals as the concentration reference and are shown in mean and standard deviations in eleven subjects. Ratios between metabolite concentrations in GM and WM were calculated to characterize GM and WM concentration differences of each metabolite.
BASE-SLIM
| |||||
---|---|---|---|---|---|
NAA | Cr | tCho | Glu+Gln | mI | |
GM | 7.48 ± 0.56 | 5.30 ± 0.70 | 1.41 ± 0.16 | 10.13 ± 2.16 | 4.77 ± 0.39 |
WM | 8.11 ± 0.83 | 4.57 ± 0.41 | 1.83 ± 0.18 | 4.16 ± 1.22 | 4.19 ± 0.42 |
| |||||
GM/WM | 0.92 | 1.16 | 0.77 | 2.44 | 1.14 |
MRSI
| |||||
---|---|---|---|---|---|
NAA | Cr | tCho | Glu+Gln | mI | |
GM | 7.67 ± 0.97 | 5.99 ± 0.52 | 1.50 ± 0.15 | 13.69 ± 1.57 | 5.52 ± 0.58 |
WM | 7.08 ± 0.72 | 4.32 ± 0.33 | 1.76 ± 0.17 | 5.10 ± 1.76 | 4.01 ± 0.57 |
| |||||
GM/WM | 1.08 | 1.39 | 0.85 | 2.69 | 1.38 |