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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Neuropharmacology. 2016 Mar 2;107:1–8. doi: 10.1016/j.neuropharm.2016.03.003

Fig. 4.

Fig. 4

CIE augments GABA transmission in neurons from Alk +/+ but not Alk −/− mice. Mean sIPSC frequency in CeA neurons from Alk +/+ (A) and Alk −/− (B) mice that were ethanol-naïve, underwent air exposure and 2BC (2-bottle), or CIE-2BC (chronic EtOH). Alk +/+ mice showed increased sIPSC frequency after CIE, whereas Alk −/− mice did not. Note that the sIPSC frequency in Alk −/− mice was higher than Alk +/+ mice under all conditions and compared to the sIPSC frequency in ethanol-vapor treated Alk +/+ mice. Data are expressed as the mean ± SEM. *p < 0.05.