Appendix A.

Alerts

Citation	Lawton, (2011)[22]	Cooper, (2010)[21]
Clinical Domain	Medications	COPD
Reminder Purpose/Technology Intervention	Alert to adverse drug reactions/Mobile phone, web-based application	Weather alert/Automated telephone:
Study Objective	Sends customized alert on adverse drug event risk, tailored to participant’s age and condition	Provided calls to participants to warn when the weather forecast for the next few weeks is ‘elevated’.
Study n	18	17
Study Design	Semi-structured interview	Qualitative semi-structured telephone interviews
Setting	Denmark, hospital clinic in Copenhagen	England, hospital system
Measurement	Compared usefulness and utility of web-based application, telephone alert, and paper based medication list.	Qualitative interview
Results	The patients found the paper-based medication list useful and comprehensive for control of own prescribed medication. The Web-based prototype also proved to be useful, but drug and lab values were hard to correlate, and the alerts were hard to understand. The cell phone-based prototype proved less useful as the patients were challenged to vision the applicability of the system	Patients perceived the telephone service as appropriate for information delivery. There was variation on perceived usefulness as related to reassurance, medication reminders, and reliability of weather forecasts information. Primary care staff perceived the service as successful, but felt that it lacked participation by hard-to-reach groups (non-English speaking, mild COPD patients).