Table 1.
Characteristics of statin users and non-users in patients with inflammatory bowel diseases
Characteristic | Statin users (n = 1,376) | Statin non-users (n = 9,625) | p-value |
---|---|---|---|
Current age (in years) [Median (IQR)] | 67 (58 – 76) | 42 (29 – 56) | < 0.001 |
Age at first IBD contact (in years) [Median (IQR)] | 59 (50 – 68) | 36 (24 – 50) | < 0.001 |
Duration since first IBD contact (in years) [Median (IQR)] | 7 (3 – 11) | 5 (2 – 9) | < 0.001 |
Female (%) | 45 | 54 | < 0.001 |
White race (%) | 89 | 85 | < 0.001 |
Type of IBD – ulcerative colitis (%) | 62 | 49 | < 0.001 |
Charlson score [Mean(SD)] | 5.8 (3.7) | 2.1 (2.7) | < 0.001 |
Co-existing PSC (%) | 2 | 2 | 0.68 |
Medical therapies | |||
Immunomodulator (%) | 20 | 25 | < 0.001 |
Anti-TNF biologics (%) | 6 | 13 | < 0.001 |
Colonoscopy within 3 years (%) | 40 | 35 | < 0.001 |
C-Reactive protein [Median (IQR)] (in mg/L) | 5 (2 – 16) | 4.4 (2 – 14.4) | 0.11 |
Ever smoker (%) | 86 | 55 | < 0.001 |