Table 3.
Characteristics of colorectal cancer in statin users and non-users
| Characteristic | Statin users (n = 30) | Statin non-users (n = 287) | p-value |
|---|---|---|---|
| Age at cancer diagnosis [Median(IQR)] (in years) | 67 (63 – 73) | 55 (45 – 65) | < 0.001 |
| Age at first IBD contact [Median(IQR)] (in years) | 64 (56 – 68) | 53 (41 – 64) | < 0.001 |
| Mean duration since first IBD contact (in years) | 6 | 3 | < 0.001 |
| Female (%) | 33 | 42 | 0.35 |
| White (%) | 93 | 89 | 0.48 |
| Ulcerative colitis (%) | 80 | 46 | < 0.001 |
| Co-existing PSC (%) | 7 | 5 | 0.67 |
| Medical therapies | |||
| Immunomodulator (%) | 23 | 16 | 0.31 |
| Anti-TNF biologics (%) | 0 | 7 | 0.14 |
| C-Reactive protein [Median(IQR)] (in mg/L) | 5.4 (0.5 – 11.8) | 7.1 (3.7 – 29.4) | < 0.001 |
| Ever smoker (%) | 93 | 71 | 0.008 |
| Died (%) | 30 | 27 | 0.74 |