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. Author manuscript; available in PMC: 2017 Jul 30.
Published in final edited form as: Psychiatry Res. 2016 May 7;241:315–322. doi: 10.1016/j.psychres.2016.04.120

Fig. 3.

Fig. 3

Increases in Nuclear Factor - Kappa B (NF-κB) Activation following TNF-alpha Stimulation in Adolescents with Bipolar Disorder, Major Depressive Disorder (MDD), or No Psychiatric History (Controls). Notes. MDD = Major Depressive Disorder; PBMC= Peripheral Blood Mononuclear Cells. Values are mean (+ standard error) changes in fluorescence intensity scores (stimulated MFI - unstimulated MFI) in monocyte, lymphocyte and total peripheral blood mononuclear cell populations. The bipolar and MDD groups both had greater increases in stimulated monocyte levels than controls (p<0.05). The bipolar group also had greater increases in stimulated peripheral blood mononuclear cells than controls (p<0.05). The two mood groups did not significantly differ in increases in NF-κB activation following stimulation.