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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Neuropharmacology. 2016 Mar 3;107:40–48. doi: 10.1016/j.neuropharm.2016.02.036

Fig. 4.

Fig. 4

Ethanol consumption by AS-PKCε mice. (A) AS-PKCε mice were habituated to vehicle injections and allowed to achieve a stable baseline level of drinking. Arrows point to days when animals received vehicle injections. 1-NA-PP1 reduced ethanol consumption (B) and this effect was reversible since it was no longer present 48 hours after administration of 1-NA-PP1 (C). (D) 1-NA-PP1 did not alter preference for ethanol over water or water intake (E) 1-NA-PP1 (30 mg/kg) reduced saccharin intake (F), but not quinine (G) intake.(H) 1-NA-PP1 (30 mg/kg) did not alter ethanol clearance. *P < 0.05, Dunnett’s test; n = 18 per group (A-E), n = 14 per group (F and G), n = 7 per group (H).