Table 2.
Frequency of NMS and mean NMSS scores in PSP and HC.
| NMSS domain | Frequency of NMS | P value | NMSS score | P value | ||
|---|---|---|---|---|---|---|
| PSP, n (%) | HC, n (%) | PSP, mean ± SD | HC, mean ± SD | |||
| Cardiovascular | 5 (18.5) | 5 (18.5) | 1.000 | 1.2 ± 3.5 | 0.3 ± 0.6 | 0.497 |
| Sleep/fatigue | 27 (100) | 16 (59.3) | <0.001∗ | 12.4 ± 9.5 | 3.0 ± 4.5 | <0.001∗ |
| Mood/apathy | 27 (100) | 3 (11.1) | <0.001∗ | 16.6 ± 15.4 | 0.9 ± 3.1 | <0.001∗ |
| Perceptual problems/hallucinations | 4 (14.8) | 2 (7.4) | 0.669 | 0.2 ± 0.6 | 0.2 ± 0.8 | 0.705 |
| Attention/memory | 26 (96.3) | 16 (59.3) | 0.002∗ | 7.1 ± 7.4 | 1.7 ± 2.5 | <0.001∗ |
| Gastrointestinal | 23 (85.2) | 8 (29.6) | <0.001∗ | 7.1 ± 7.0 | 1.1 ± 2.1 | <0.001∗ |
| Urinary | 20 (74.1) | 18 (66.7) | 0.766 | 4.7 ± 5.5 | 3.0 ± 3.3 | 0.288 |
| Sexual dysfunction | 25 (92.6) | 13 (48.1) | 0.001∗ | 6.5 ± 6.7 | 1.8 ± 1.9 | 0.001∗ |
| Miscellaneous | 23 (85.2) | 10 (37.0) | 0.001∗ | 5.7 ± 5.6 | 1.8 ± 3.9 | 0.002∗ |
| Total | 27 (100) | 25 (92.6) | 0.491 | 61.6 ± 31.5 | 13.7 ± 11.8 | <0.001∗ |
NMS: nonmotor symptoms. NMSS: Nonmotor Symptoms Scale. PSP: progressive supranuclear palsy. HC: healthy control. SD: standard deviation. ∗Significant difference.