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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Neurobiol Aging. 2016 May 2;44:185–196. doi: 10.1016/j.neurobiolaging.2016.04.019

Figure 4. MALDI-TOF mass spectrometry analysis of insoluble Aβ peptides in AD and aged squirrel monkey neocortices.

Figure 4

Panel A: Aβ spectra obtained from occipital cortical extracts of two aged-squirrel monkey specimens, Ss1 (top) and Ss2 (bottom). Panel B: Aβ spectra obtained from temporal and occipital extracts of two AD patients (AD3, top; AD4, bottom). Labeled peaks correspond to full-length, truncated, or post-translationally-modified Aβ peptides. Panel C: Comparative list of theoretical and experimental m/z values for all AD and monkey samples tested As a whole, the spectrometric pattern of Aβ peptides in aged squirrel monkeys was similar to that of the AD group.