Table 2.
Cinnamon bark content (g/day) | Coumarin content (mg/day) | Coumarin content (mg/g of cinnamon bark) | n | |
---|---|---|---|---|
Cinnamon bark | 4.0 | 12.07 | 3.02 | 1 |
Keishibukuryogankayokuinin (TJ-125) | 4.0 | 5.63 ± 0.94 | 1.41 ± 0.24 | 3 |
Mokuboito (TJ-36) | 3.0 | 4.00 | 1.33 | 1 |
Keishibukuryogan (TJ-25) | 3.0 | 2.92 ± 0.09 | 0.97 ± 0.03 | 3 |
Ryokeijutsukanto (TJ-39) | 4.0 | 2.80 ± 0.96 | 0.70 ± 0.24 | 3 |
Goreisan (TJ-17) | 1.5 | 2.48 ± 0.07 | 1.65 ± 0.05 | 3 |
Nyoshinsan (TJ-67) | 2.0 | 2.32 | 1.16 | 1 |
Kakkonto (TJ-1) | 2.0 | 2.00 ± 0.07 | 1.00 ± 0.03 | 3 |
Kakkonkajutsubuto (S-07) | 2.0 | 1.80 ± 0.17 | 0.90 ± 0.09 | 3 |
Saireito (TJ-114) | 2.0 | 1.15 | 0.57 | 2 |
Saikokeishikankyoto (N11) | 3.0 | 1.13 | 0.38 | 1 |
Keishininjinto (TJ-82) | 4.0 | 1.09 ± 0.54 | 0.27 ± 0.14 | 3 |
Saikokeishito (N10) | 2.5 | 1.03 | 0.41 | 1 |
Saikokeishito (TJ-10) | 2.0 | 0.86 ± 0.20 | 0.43 ± 0.10 | 3 |
Saikokeishikankyoto (TJ-11) | 3.0 | 0.79 ± 0.05 | 0.26 ± 0.02 | 3 |
Saikokaryukotsuboreito (TJ-12) | 3.0 | 0.69 ± 0.04 | 0.23 ± 0.01 | 3 |
Saikokaryukotsuboreito (N12) | 3.0 | 0.66 | 0.22 | 1 |
Hachimijiogan (TJ-7) | 1.0 | 0.65 ± 0.22 | 0.65 ± 0.22 | 3 |
Keishikaryojutsubuto (SG-18R) | 4.0 | 0.55 ± 0.14 | 0.14 ± 0.03 | 3 |
Keishikaryukotsuboreito (TJ-26) | 4.0 | 0.51 ± 0.23 | 0.13 ± 0.06 | 3 |
Shoseiryuto (TJ-19) | 3.0 | 0.48 ± 0.22 | 0.16 ± 0.07 | 3 |
Keishikajutsubuto (TJ-18) | 4.0 | 0.46 | 0.11 | 2 |
Maoto (TJ-27) | 4.0 | 0.41 ± 0.03 | 0.10 ± 0.01 | 3 |
Kumibinroto (N311) | 3.0 | 0.36 ± 0.02 | 0.12 ± 0.01 | 3 |
Tokikenchuto (TJ-123) | 4.0 | 0.34 ± 0.26 | 0.08 ± 0.07 | 3 |
Shakanzoto (TJ-64) | 3.0 | 0.26 ± 0.05 | 0.09 ± 0.02 | 3 |
Keishito (TJ-45) | 4.0 | 0.26 ± 0.01 | 0.06 ± 0.00 | 3 |
Juzentaihoto (TJ-48) | 3.0 | 0.24 ± 0.04 | 0.08 ± 0.01 | 3 |
Jidabokuippo (TJ-84) | 3.0 | 0.24 ± 0.04 | 0.08 ± 0.01 | 3 |
Hachimigan | 1.0 | 0.22 ± 0.02 | 0.22 ± 0.02 | 3 |
Tokishigyakukagoshuyushokyoto (TJ-38) | 3.0 | 0.15 | 0.05 | 1 |
Goshakusan (TJ-63) | 1.0 | ND | ND | 2 |
Goshajinkigan (TJ-107) | 1.0 | ND | ND | 3 |
Keishikaogito (TY-026) | 4.0 | ND | ND | 3 |
Mean ± SD | 1.43 ± 0.20 | 0.50 ± 0.06 |
n, number of production lots for HPLC analysis; ND, not detected; The coumarin content and coumarin content included in 1 g of cinnamon bark are shown as mean ± SD for n = 3, mean for n = 2, and the measured value for n = 1.