Table 4.
Univariate and multivariate analyses of predictive factors for AKI
| Variable | Univariate analysis |
Multivariate analysis |
|
|---|---|---|---|
| P Value |
Odds ratio (95% Confidence interval) |
P Value |
|
| Demographics | |||
| Age (years)a | 0.027 | 1.030 (1.001–1.050) | 0.040 |
| Female sex (yes vs no) | 0.119 | ||
| Clinical variables | |||
| Cirrhosis (yes vs no) | 0.202 | ||
| Portal hypertension (yes vs no) | 0.827 | ||
| ASA ≥ III (yes vs no) | 0.092 | 0.411 | |
| Chronic pulmonary disease (yes vs no) | 0.054 | 0.190 | |
| Cardiovascular disease (yes vs no) | 0.019 | 0.210 | |
| Diabetes mellitus (yes vs no) | 0.722 | ||
| Chronic kidney injury (yes vs no) | 0.005 | 0.07 | |
| Body mass index ≥ 30 kg/m2 (yes vs no) | 0.887 | ||
| eGFR (ml/min/1.73 m2)a | 0.502 | ||
| MELD scorea | 0.013 | 1.000 (1.001–1.050) | 0.040 |
| BCLC stage (A vs B or C) | 0.160 | ||
| Intraoperative variables | |||
| Extent of liver resection (minor vs major) | 0.002 | 2.7 (1.5–5.0) | 0.001 |
| Vascular clamping (yes vs no) | 0.318 | ||
| Clamping time (min)a | 0.163 | ||
| Packed red blood cell transfusion (yes vs no) | 0.002 | 0.30 | |
| Duration of operation > 300 min (yes vs no) | 0.008 | 2.4 (1.0–5.9) | 0.05 |
Footnotes: ASA, American Society of Anesthesiologists; eGFR, estimated glomerular filtration rate; MELD, Model for End-stage Liver Disease; BCLC, Barcelona Clinic Liver Cancer.
a
Continuous variables.