Table 5.

Univariate and multivariate analyses of risk factors for postoperative mortality

Variable	Univariate analysis	Multivariate analysis
P Value	Odds ratio (95% Confidence interval)	P Value
Demographics
Age (years)a	0.085		0.410
Female sex (yes vs no)	0.006		0.471
Clinical variables
Cirrhosis (yes vs no)	0.024		0.252
Portal hypertension (yes vs no)	0.475
ASA ≥ III (yes vs no)	0.007		0.880
Chronic pulmonary disease (yes vs no)	0.698
Cardiovascular disease (yes vs no)	0.004		0.190
Diabetes mellitus (yes vs no)	0.090	3.2 (1.3–8.2)	0.015
Chronic kidney injury (yes vs no)	0.017		0.500
Body mass index ≥ 30 kg/m2 (yes vs no)	0.359
eGFR (ml/min/1.73 m2)a	0.778
MELD scorea	<0.002	1.2 (1.0–1.3)	0.018
BCLC stage (A vs B or C)	0.006		0.459
Intra-operative variables
Extent of liver resection (minor vs major)	0.082		0.768
Vascular clamping (yes vs no)	0.027		0.633
Clamping time (min)a	0.053		0.995
Packed red blood cell transfusion (yes vs no)	<0.001	2.9 (1.2–6.7)	0.016
Duration of operation > 300 min (yes vs no)	0.37
Complications
AKI (yes vs no)	<0.001	6.6 (2.8–15.5)	<0.001
Liver failure (yes vs no)	<0.001	5.7 (1.8–17.6)	0.003
Ascites (yes vs no)	<0.001		0.785
Biliary fistula (yes vs no)	0.952
Infectious complications (yes vs no)	<0.001		0.696
Pulmonary complications (yes vs no)	<0.005		0.593

Footnotes: ASA, American Society of Anesthesiologists; eGFR, estimated glomerular filtration rate; APRI, aminoaspartate transferase to platelet ratio index; MELD, Model for End-stage Liver Disease; BCLC, Barcelona Clinic Liver Cancer; AKI, acute kidney injury; KDIGO, Kidney Disease Improving Global Outcomes.

^aContinuous variables.