Table 2.
Comparison between adults and children of previous surgical and/or endoscopic procedures, clinical presentation, coexistent hepatobiliary and pancreatic (HBP) disease according to BDC Todani subtype (please refer to Supplementary Table 2 for full results)
| Whole series |
p value |
Type I+IVB BDC |
p value |
Type IVA BDC |
p value |
||||
|---|---|---|---|---|---|---|---|---|---|
| Children n = 98 | Adults n = 216 | Children n = 79 | Adults n = 164 | Children n = 19 | Adults n = 52 | ||||
| Prior surgical and/or radiological and/or endoscopic procedures | |||||||||
| • Prior biliary tract surgery and/or endoscopic procedures | 11 (11.2%) | 103 (47.7%) | <0.0001 | 10 (12.7%) | 72 (43.9%) | <0.0001 | 1 (5.3%) | 31 (59.6%) | <0.0001 |
| • Surgery alone | 4 (4.1%) | 62 (28.7%) | <0.0001 | 4 (5.1%) | 45 (27.4%) | <0.0001 | 0 | 17 (32.7%) | 0.0035 |
| • Cyst-enterostomy | 0 | 22 (10.2%) | 0.0011 | 0 | 16 (9.8%) | 0.0041 | 0 | 6 (11.5%) | 0.1824 |
| Clinical presentation | |||||||||
| • No symptom | 8 (8.2%) | 33 (15.3%) | 0.0803 | 6 (7.6%) | 27 (16.5%) | 0.0587 | 2 (10.5%) | 6 (11.5%) | 1.0000 |
| • Isolated pain | 47 (48%) | 86 (39.8%) | 0.1760 | 36 (45.6%) | 70 (42.7%) | 0.6708 | 11 (57.9%) | 16 (30.8%) | 0.0371 |
| • Cholangitis | 17 (17.3%) | 78 (36.1%) | 0.0008 | 15 (19.0%) | 49 (29.9%) | 0.0710 | 2 (10.5%) | 29 (55.8%) | 0.0007 |
| • Pancreatitis | 25 (25.5%) | 38 (17.6%) | 01045 | 18 (22.8%) | 33 (20.1%) | 0.6330 | 7 (36.8%) | 5 (9.6%) | 0.0120 |
| • Abdominal mass | 30 (30.6%) | 3 (1.4%) | <0.0001 | 22 (27.8%) | 2 (1.2%) | <0.0001 | 8 (42.1%) | 1 (1.9%) | <0.0001 |
| • Jaundice | 42 (42.9%) | 46 (21.3%) | <0.0001 | 34 (43.0%) | 31 (18.9%) | <0.0001 | 8 (42.1%) | 15 (28.8%) | 0.2906 |
| • Complicated presentation | 35 (35.7%) | 109 (50.5%) | 0.0151 | 27 (34.2%) | 77 (47.0%) | 0.0594 | 8 (42.1%) | 32 (61.5%) | 0.1438 |
| Coexistent hepatobiliary and pancreatic (HBP) diseases | |||||||||
| • Liver disease | 2(2%) | 23 (10.6%) | 0.0090 | 2 (2.5%) | 8 (4.9%) | 0.5061 | 0 | 15 (28.8%) | 0.0072 |
| • Biliary disease | 14 (14.3%) | 77 (35.6%) | 0.0001 | 12 (15.2%) | 49 (29.8%) | 0.0134 | 2 (10.5%) | 28 (53.4%) | 0.0011 |
| ○ stones | 13 (13.3%) | 51 (23.6%) | 0.0350 | 11 (13.9%) | 30 (18.3%) | 0.3943 | 2 (10.5%) | 21 (40.4%) | 0.0173 |
| ○ Synchronous cancer | 0 | 25 (11.6%) | 0.0118 | 0 | 19 (11.6%) | 0.0016 | 0 | 6 (11.5%) | 0.1777 |
| • Pancreatic disease | 5 (5.1%) | 15 (6.9%) | 0.5356 | 4 (5.1%) | 10 (6.1%) | 1.0000 | 1 (5.3%) | 5 (9.6%) | 1.0000 |