Table 3.

Comparison between adults and children of short- and long-term outcome and preoperative treatment and types of surgery according to BDC Todani subtype (please refer to Supplementary Table 3 for full results)

	Whole series		p value	Type I+VB BDC		p value	Type IVA BDC		p value
	Children n = 98	Adults n = 216		Children n = 79	Adults n = 164		Children n = 19	Adults n = 52
TYPES OF SURGICAL PROCEDURES
○ Incomplete cyst excision	10 (10.2%)	29/209 (13.8%)	0.4630	4 (5.0%)	21/158 (13.3%)	0.0702	6 (31.6%)	8/51 (15.7%)	0.1393
ASSOCIATED PROCEDURES
○ Hepatectomy	1 (1%)*	28 (12.9%)	0.0002	0	6 (3.7%)	0.4327	1 (5.2%)	22***(42.3%)	0.0031
○ Pancreatoduodenectomy	1 (4%)	12 (5.5%)	0.0707	0	8 (4.9%)	0.0564	1 (5.3%)	4 (7.7%)	1.0000
○ Cancer excision	0	23 (10.6%)	0.0002	0	18 (10.9%) $	0.0003	0	5 (9.6%)	0.329
• Combined resection°	2 (2%)	51 (23.6%)	<0.0001	0	25(15%)	<0.0001	2 (10%)	26 (50%)	0.0509
EARLY POSTOPERATIVE OUTCOME
• Mortality rate (%)	0	1 (0.5%)	1.0000	0	1 (0.6%)	1.0000	0	0	1.0000
• Complications rate (%)	20 (20.4%)	104 (48.1%)	<0.0001	15 (19%)	72 (43.9%)	0.0001	5 (26.3%)	32 (61.5%)	0.0085
o Grade III-IV	4 (4.1%)	49 (22.7%)	<0.0001	2 (2.5%)	33 (20.1%)	0.0003	2 (10.5%)	16 (30.7%)	0.1238
LONG-TERM OUTCOME	n=80 (82%)	n=178 (82.4%)		n=66 (83.5%)	n=132 (80.5%)		n=14 (74%)	n=46 (88.5%)
• Median follow-up (months)	42 (4-732)	36 (4-292)	0.0619	39.5 (4-372)	36.5 (4-292)	0.2060	45 (8-351)	24.5 (4-228)	0.1592
• Mayo clinic score
○ Excellent + Good	73 (91.2%)	130 (73%)	0.0009	61 (92.4%)	102 (77.3%)	0.0084	12 (85.7%)	27 (58.7%)	0.1080
○ Fair + Poor	7 (8.8%)	48 (27%)		5 (7.6%)	30 (22.7%)		2 (14.3%)	19 (41.3%)
• Repeat procedures	5/78	39/161	<0.0001	3/64	25/118	0.0066	2/14	14/43	0.3347

*One total hepatectomy for transplantation in a child.

**Two total hepatectomy for transplantation in adults.

***Two patients underwent biliary stone extraction.

$ A secondary central hepatectomy was performed after good response of chemotherapy.