Table 4.

Presentation of synchronous cancer according to Todani subtype of bile duct cyst (BDC)

	Type I+IVb BDC	Type IVA BDC	p value
Patients with cancer	19	6	0.8072
Median age (years)	47 (22–70)	51 (30–67)	0.8622
Previous cyst enterostomy	n = 5	n = 1	1.0000
Location of cancer			0.8915
• Gallbladder	n = 7	n = 0
• Extrahepatic bile duct	n = 5	n = 3
• Intrahepatic bile duct	n = 0	n = 3
• BDC	n = 6	n = 0
• Pancreas	n = 1	n = 0
Presence of pancreatobiliary malunion			0.9796
• Not explored	n = 6	n = 3
• Abnormal	n = 10	n = 1
• Normal	n = 3	n = 2
Type of surgery			0.5996
• No resection (carcinomatosis)	n = 1	n = 1
• BDC resection	n = 7	n = 0
• BDC resection + hepatectomy	n = 6a	n = 3
• BDC resection + pancreaticoduodenectomy	n = 5	n = 2b
Mortality and Morbidity			0.8859
• Grade 1	n = 3	n = 1
• Grade 2	n = 2	n = 1
• Grade 3	n = 4	n = 1
• Grade 4	n = 0	n = 1
• Grade 5 (death)	n = 1	n = 0
Staging of tumour (UICC)c	–		0.9144
• Stage 0	n = 2	n = 1
• Stage IA	n = 3	n = 1
• Stage IB	n = 5	n = 1
• Stage IIA	n = 4	n = 1
• Stage IIB	n = 3	n = 1
• Stage III	n = 0	n = 0
• Stage IV	n = 2	n = 1
Median follow-up time (months) (range)	12.5 (3–34)	12 (6–88)	1.0000
Status at final follow-up			0.7472
• Alive without complications	n = 9	n = 3
• Alive with complications	n = 1	n = 1
• Alive with cancer recurrence	n = 1	n = 0
• Death related to cancer	n = 6	n = 2
• Death related to disease complications	n = 1	n = 0
• Death not related to disease complications	n = 0	n = 0

^aOne patient underwent central hepatectomy 6 months after chemotherapy.

^bOne patient underwent pancreatectomy+hepatectomy.

^cUICC staging (www.uicc.org) 7eme edition distal extrahepatic duct BDC bile duct cyst.