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. 2016 May 7;18(6):549–556. doi: 10.1016/j.hpb.2016.04.003

Table 3.

Factors associated with postoperative hepatocellular carcinoma recurrence and hepatocellular carcinoma-related death using multivariate Cox regression analysis

Variables HR 95% CI P value
Risk of tumor recurrence
 HBV DNA load (≥50 IU/ml vs <50 IU/ml) 1.11 0.56–2.21 0.757
 Anti-virus treatment (yes vs no) 0.70 0.38–1.31 0.267
 Tumor diameter (≥10 cm vs <10 cm) 1.22 0.69–2.17 0.482
 Tumor number (multiple vs single) 1.58 0.79–3.17 0.196
 Type of hepatectomy (major vs minor) 1.48 0.84–2.63 0.178
 Hilar clamping time (≥18 min vs <18 min) 1.69 1.03–2.75 0.036*
 Neoadjuvant radiotherapy (yes vs no) 0.36 0.19–0.70 0.002*
Risk of tumor-related death
 Tumor diameter (≥10 cm vs <10 cm) 1.65 0.81–3.36 0.164
 Type of hepatectomy (major vs minor) 1.45 0.71–2.99 0.311
 Neoadjuvant radiotherapy (yes vs no) 0.32 0.18–0.57 0.000*

HR: hazard ratio; CI: confidential interval; HBV, hepatitis B virus.

*P < 0.05.