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. 2016 Jun 13;138(8):0810011–08100111. doi: 10.1115/1.4033673

Table 6.

Sensitivity of knee contact force predictions to changes in each type of model parameter values, starting from the Approach A solution (top) and the Approach B solution (bottom). Only one type of parameter was changed at a time, keeping all other types at the values from the original approach. Highlighted rows in gray contain original results obtained from Approach A (top) and Approach B (bottom). Numbers highlighted in bold indicate largest changes from original approach.

Starting from approach A Quantity Medial Lateral Total
Original approach A solution R2 0.97 0.88 0.96
RMSE 52.62 56.63 92.80
Changed loM and lsT scale factors R2 0.84 1.02 0.44
RMSE 136.45 239.47 358.78
Changed moment arm deviations R2 0.61 -0.19 0.78
RMSE 209.48 170.52 222.50
Changed activation scale factors R2 0.65 0.09 0.86
RMSE 201.15 156.03 174.70
Changed SV weights R2 0.94 0.78 0.91
RMSE 84.13 76.53 132.77
Starting from approach B Quantity Medial Lateral Total
Original approach B solution R2 0.10 −3.43 −0.36
RMSE 322.73 347.78 559.95
Changed loM and lsT scale factors R2 0.38 −0.33 0.41
RMSE 260.80 189.92 362.62
Changed moment arm deviations R2 −0.46 −1.78 −0.08
RMSE 413.12 283.15 499.97
Changed activation scale factors R2 0.53 −1.53 0.20
RMSE 232.28 267.10 430.10
Changed SV weights R2 0.45 −3.87 −0.10
RMSE 255.20 363.38 503.18