Table 2.
Effect of fish oil and placebo on glutathione redox system
| Baseline | 3 months | 6 months | 9 months | 12 months | ||
|---|---|---|---|---|---|---|
| GSH (mM) | Fish oil | 0.03±0.02 | 0.04±0.02 | 0.03±0.02 | 0.04±0.03 | 0.03±0.02 |
| Control | 0.04±0.02 | 0.04±0.02 | 0.03±0.02 | 0.04±0.02 | 0.03±0.02 | |
| GSSG (mM) | Fish oil | 0.02±0.01 | 0.03±0.02 | 0.04±0.02 | 0.06±0.03 | 0.05±0.03 |
| Control | 0.02±0.01 | 0.04±0.01 | 0.03±0.01 | 0.06±0.04 | 0.06±0.03 | |
| GSH/GSSG | Fish oil | 2.87±2.7 | 1.57±1.4 | 1.22±1.3 | 1.36±1.7 | 1.06±1.0 |
| Control | 3.45±3.2 | 1.96±2.0 | 1.34±2.2 | 1.43±2.3 | 1.03±1.7 | |
| GR (U/L) | Fish oil | 342.7±170.9 | 606.5±518.9 | 439.8±232.2 | 468.4±222.2 | 471.8±312.8 |
| Control | 330.4±197.7 | 565.8±420.2 | 589.8±444.3 | 529.2±285.0 | 570.9±455.6 |
Data expressed in mean and standard deviation (SD), Mann-Whitney U test. Reduced glutathione (GSH), oxidized glutathione (GSSG), GSH/GSSG ratio, glutathione reductase (GR).