Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effect of sgk2 on the kinetics of hOAT1-mediated PAH transport. COS-7 cells were co-transfected with hOAT1 and the constitutive active form of sgk2 (CA-sgk2), or with hOAT1 and control vector. Initial uptake (3 min) of [3H] PAH was measured at the concentration of 5-200 µM. The data represent uptake into hOAT1-transfected cells minus uptake into mock cells (parental COS-7 cells). Values are means ± S.E. (n = 3). V, velocity; S, substrate concentration.
