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. 2016 Jun 20;6:28331. doi: 10.1038/srep28331

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(A) Representative immunohistochemical staining of Cyt c and GFP in single axon of sciatic nerves in Atf3:BAC Tg and Drp1 CKO mice at 7 days after injury. (B) Frequency distribution of Cyt c- and GFP- stained mitochondrial length in control and injured nerves, respectively, using Atf3:BAC Tg (375 mitochondria in four mice for control side, 483 mitochondria in four mice for injured side) and Drp1 CKO mice (406 mitochondria in four mice for control side, 1057 mitochondria in seven mice for injured side) at 7 days after sciatic nerve injury. (C) Number of mitochondria per 10 μm² of axons was counted at 7 days after injury in Atf3:BAC Tg (n = 4–6 mice) and Drp1 CKO mice (n = 4–7 mice). Data are means ± SEM. *p < 0.001. BAC Tg; Atf3:BAC Tg mice, CKO; Drp1 conditional knockout mice, Scale bars, 5 μm in (A).