Figure 5.
Cytotoxicity results at 9 and 24 h post-exposure for A) apical washes and B) basolateral medium. O3 and aged SynUrb54 induced statistically significant increases in LDH compared to air in A549 cells in the basolateral medium. In the apical wash, a significant decrease in LDH is observed at 24 h only after O3 exposure when compared to clean air exposures but not SynUrb54. No statistically significant changes were observed with EpiAirway™ cells. An asterik (*) represents significant difference over air exposure. A pound sign (#) represents significant difference in SynUrb54 compared to O3.