Table 3. Adjusted hazards ratios with 95% confidence intervals for the risk factors of local recurrence in patients with primary giant cell tumor of bone around the knee, by sex.

Risk factors	Reference	Men	P1	Women	P2
Age	—	1.00 (0.96, 1.03)	0.970	1.00 (0.96, 1.03)	0.796
Side	Left side	0.69 (0.36, 1.33)	0.271	1.13 (0.53, 2.43)	0.753
Location	Distal femur
Proximal tibia		0.62 (0.33, 1.39)	0.150	1.38 (0.62, 3.08)	0.432
Proximal fibula		49.84 (4.42, 562.56)	0.002	0	0.993
Campanacci grade	I
II		0.76 (0.24, 2.36)	0.629	0.38 (0.11, 1.26)	0.379
III		1.56 (0.50, 4.90)	0.488	0.53 (0.16, 1.68)	0.276
Pathologic fracture	No	0.67 (0.32, 1.39)	0.282	0.44 (0.63, 3.27)	0.388
Surgical technique	En-bloc resection
Intralesional curettage		15.73 (4.11, 60.27)	<0.0001	10.76 (2.98, 38.92)	<0.0001
Curettage combined resection		9.46 (2.69, 32.27)	<0.0001	3.60 (1.00, 13.15)	0.05