Figure 3.

Total time sniffing novel and familiar objects were measured in the novel object recognition task. This task was performed with no delay or 1-h delay following exposure to familiar objects. Female HIV-1 Tg rats spent less time sniffing all objects (A). Female Tg rats spent a reduced difference in time sniffing the novel vs. familiar object compared to female WT control rats (B). Male HIV-1 Tg rats spent less time sniffing all objects (C), and genotype, stress, and time interacted to impact the difference in time spent sniffing the novel vs. familiar object in males (D). Data are presented as mean ± SEM. # denotes a main effect of HIV-1 Tg genotype. α = 0.05.