Table 6.
Blood vessel length and density were estimated using the Spaceballs probe (Stereo Investigator).
| Region | Measure | Genotype | n | Mean ± SEM | T statistic | p-value |
|---|---|---|---|---|---|---|
| Hippocampus | Length (μm) | WT | 5 | 5.653 × 106 ± 439454 | t9 = 1.667 | 0.1298 |
| Tg | 6 | 4.743 × 106 ± 339171 | ||||
| Density (μm/μm3) | WT | 5 | 2.025 ± 0.2465 | t9 = 1.007 | 0.3401 | |
| Tg | 6 | 1.774 ± 0.1019 | ||||
| PFC | Length (μm) | WT | 3 | 4.380 × 106 ± 920262 | t6 = 0.2436 | 0.8157 |
| Tg | 5 | 4.633 × 106 ± 595337 | ||||
| Density (μm/μm3) | WT | 3 | 2.551 ± 0.08156 | t6 = 1.064 | 0.3281 | |
| Tg | 5 | 3.164 ± 0.4294 | ||||
| Amygdala | Length (μm) | WT | 5 | 3.591 × 106 ± 189420 | t9 = 0.2770 | 0.788 |
| Tg | 6 | 3.700 × 106 ± 320519 | ||||
| Density (μm/μm3) | WT | 5 | 1.280 ± 0.07705 | t9 = 1.044 | 0.3237 | |
| Tg | 6 | 1.402 ± 0.08481 |
A student’s t-test was used to compare vessel length and density between WT and HIV-1 Tg rats in the hippocampus, PFC, and amygdala. Mean, SEM, and test statistics are shown. HIV-1 Tg rats did not exhibit significantly different blood vessel length or density in any region. α = 0.05.